Fig. 7. Reconstruction of WMS-1410 (2): A NO₂ moiety was introduced in 8-position instead of the 7-OH-moiety (6). The phenol was replaced bioisosterically by a benzoxazolone system (7). An O-atom (8), a carbonyl moiety (9) and an F-atom (9, 10) were introduced into the 4-phenylbutyl side chain.